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Fibrovien Solution 1% - 1vial x 5ml, Injection for Sclerotherapy
The introduction of sodium tetradecyl sulfate into the lumen of a varicose vein leads to damage to the vascular endothelium, followed by fibrosis, adhesion of the vein walls and its irreversible obliteration.
Subsequent adequate compression of the section of the vein intended for sclerotherapy contributes to the formation of a dense sclerothrombus of the smallest possible diameter.
In the absence of compression of the vein after the administration of the drug, a large thrombus may form in its lumen, and the severity of fibrosis will be insignificant.
Indications:
Sclerosis during compression therapy of varicose veins of the lower extremities, telangiectasias.
Active ingredients: Sodium tetradecyl sulfate
The drug can only be used by doctors who own the technique of sclerotherapy
Ingredients
How to Use
Dosage and administration:
Intravenous injection into the lumen of an isolated section of a vein previously freed from blood, followed by immediate long-term compression of this site.
To obtain the maximum therapeutic effect and reduce the risk of developing adverse events (AEs), the following basic principles of compression sclerotherapy should be observed:
- Before administering the drug, it is necessary to assess the condition of the deep veins and the presence of valvular insufficiency
- Before conducting a course of venous sclerosing therapy, it is necessary to conduct a trial administration of the drug to identify possible individual intolerance
- The very first injection of Fibro-Vane is made at the most distal of the intended points. A compression bandage should be applied immediately, before the drug is injected into the adjacent target point.
- The sclerosant should be administered immediately after the release of blood from the intended area of the vein.
- The sclerosant should be held in an empty and isolated area of the vein for approximately 30 seconds.
- The compression bandage must be applied immediately. Compression should be adequate and maintained for 6 weeks from the date of administration of the drug at the last target point.
- Optimal compression is achieved by using elastic bandages of medium extensibility and special latex pads to provide local compression,
- To prevent a possible damaging effect on the deep vein endothelium with their subsequent thrombosis, patients are advised to walk vigorously for at least 1 hour immediately after the injection. Subsequent daily hourly walks are required.
The choice of concentration of the drug and the size of the needle depends on the diameter of the varicose vein to be treated.
Fibro-Vane solutions 2 mg/ml and 5 mg/ml are used for injection sclerotherapy of intradermal varicose veins and telangiectasias.
In the presence of an extensive widespread varicose process, injections of the solution are repeated 2-10 times at intervals of 3-5 days.
The maximum dose per treatment session is 10 ml, the recommended needle is 27 G x 1/2", 30 G x 1/2".
Fibro-vein solution 2 mg/ml: injected at the rate of 0.1-1.0 ml for every 3-5 cm of intradermal varicose vein or telangiectasia.For one session of therapy, the drug is injected into 2-6 points, 0.3-0.5 ml each (preferably 1 ml).
If it is necessary to carry out a phased sclerosing treatment, sclerosis of the superficial veins begins with the lateral branches, and the introduction into the main venous trunk is carried out last.
With combined treatment in combination with a surgical operation, they are injected into varicose tributaries (after removal of the superficial main trunks).
